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Author

Scott E. Woodman

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Jul 2026

Abstract A027: Leveraging genomic copy-number complexity in uveal melanoma to drive novel therapeutic development

Uveal Melanoma (UM) is a rare tumor characterized by activating mutations in GNAQ or GNA11, followed by a secondary mutation in BAP1, SF3B1 or EIF1AX. Notably, chromosome 3 copy-number loss, enriched among BAP1-mutant patients, is associated with an increased likelihood of metastasis. While chromosome 3 loss remains...

Johnathon L. Rose, Sanjana Srinivasan, A. Cooper et al. · 0 citations
Jul 2026

Abstract A053: Specific cancer cell and immune features mediate atezolizumab-regimen clinical benefit in anaplastic thyroid cancer (ATC) independent of BRAF or RAS oncogenic status

Specific differentiation and immune activation features are associated with longer OS, whereas mesenchymal, hypoxic, and proliferative programs are associated with shorter OS, whereas mesenchymal, hypoxic, and proliferative programs are associated with shorter OS.

Brian McKinley, Hai-Feng Zhu, Rare Tumor Initiative Team et al. · 0 citations

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