Author

Scott R. Plotkin

2 papers indexed here

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Open access Aug 2026

NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency in NF2-SWN iPSC-derived spheroid model

NF2-related schwannomatosis (NF2-SWN) is an inherited autosomal dominant disorder resulting from loss-of-function mutations in the NF2 gene, for which no effective treatment is currently available. Furthermore, truncating variants in NF2 are associated with the severest phenotype compared to in-frame or missense varian...

Gemma Casals-Sendra, Ignasi Jarne-Sanz, N. Catasús et al. · Molecular Therapy: Nucleic A... · 0 citations

Open access May 2026

A deep learning algorithm for fully automated volumetric measurement of meningioma burden

Abstract Background We sought to develop a deep learning (DL) model to enable fully automated 3D segmentation and volumetric assessment of meningioma burden with a specific emphasis on generalizing to high-grade and posttreatment meningiomas to improve interobserver variability and decrease reader time investment in tu...

Mason C. Cleveland, A. Kim, Thomas N McNeal et al. · Neuro-Oncology Advances · 0 citations