Se-Chang Kim

Dual-network gallic acid-functionalized chitosan methacryloyl/FGelMA hydrogel for diabetic wound healing via enhanced angiogenesis and inflammation modulation.

In vivo experiments reveal that the hydrogel significantly accelerated wound closure via improved re-epithelialization, collagen production, and neovascularization and modulated macrophage polarization toward M2 phenotype in full-thickness wound model in streptozotocin (STZ)-induced diabetic mice, suggesting this photocrosslinked hydrogel system can serve as a promising wound dressing for hard-to-heal chronic wounds.