Aug 2026
Mena EVH1 Interacts with PTP1B Via a Distributed Interface Without Regulating Enzymatic Activity.
The interaction between mammalian enabled protein (Mena), an actin regulatory protein, and protein tyrosine phosphatase 1B (PTP1B) is critical for maintaining epidermal growth factor receptor (EGFR) signaling homeostasis and regulating cellular motility. Mena recruits PTP1B to activated EGFR in vivo, facilitating recep...
Lanette LaComb, Sean M. Cahill, J. Bonanno et al.
· Biochemistry · 0 citations