Open access
Jul 2026
Minimal Data · Maximal Insight (MDMI): A Structure-guided Pipeline for Discovering Functional Alternatives in Peptide-Protein Interfaces
Minimal Data Maximal Insight (MDMI), a two-stage structure-guided computational pipeline that designs functional peptide variants using only a small, annotated dataset, demonstrates that structure-informed pipelines can uncover remote functional sequence space from minimal data.
P. Bayat, Spencer J. Perkins, Sebastian Clancy et al.
· bioRxiv · 0 citations