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Author

Sebastian G. Wicha

2 papers indexed here

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Open access Oct 2026

Empirical linezolid target attainment in critically ill patients: integrating local susceptibility data and dosing strategies.

Linezolid is important for treating infections caused by Gram-positive bacteria resistant to first-line agents. Severe infections often require empirical therapy before pathogen identification and susceptibility testing. This evaluation aims to compare different empirical linezolid dosing strategies in intensive care u...

J. Starp, A. Leonhardt, Jette Jung et al. · 0 citations
Open access Oct 2026

Population pharmacokinetics of piperacillin based on multicenter data to support model-informed precision dosing in critically ill women

ABSTRACT Sex-specific differences in pharmacokinetics are increasingly recognized as clinically relevant, yet most population pharmacokinetic models for antibiotics have been developed in predominantly male populations with limited transferability to female patients. This study aimed to develop and externally evaluate...

Sebastian Greppmair, S. Pesthy, M. Zoller et al. · 0 citations

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