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Author

Sebastian Pott

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Open access Oct 2026

The Human Gut Cell Atlas v1.0: A Unified, Community-Built Reference of Cellular Diversity Across the Gut

Single-cell RNA-sequencing (scRNA-seq) studies have transformed our understanding of cellular diversity in the human intestine, but differences in anatomical sampling, experimental processing and cell-type nomenclature limit comparison across datasets. Here, we present the Human Gut Cell Atlas (HGCA) V1, a community-cu...

Kyle J. Kimler, Christopher Lance, B. Bohar et al. · 0 citations
Open access Aug 2026

Cell-type-specific eQTLs underlie the genetic architecture of complex traits.

This work unbiasedly characterized cell-type-specific eQTLs by applying a variance component model to population-scale single-cell RNA-sequencing (RNA-seq) data and established eQTL cell-type specificity as a key feature of gene regulation and partly explain why known eQTLs are depleted in gene regulatory effects on co...

Minhui Chen, Xin-Pei Wang, Lena Krockenberger et al. · 1 citation

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