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Sedat Köstekci

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Open access Sep 2026

Quinine modulates PD-L1 and STAT3 in MCF-7 cells: An in silico and in vitro study

Findings indicate that quinine suppresses MCF-7 cell growth and migration by downregulating PD-L1 and STAT3 gene expression, reducing VEGF levels, and increasing TINAGL-1 levels, highlighting the compound’s potential for PD-L1 inhibition in cancer.

Fuat Karakuş, Sedat Köstekci, B. Kuzu et al. · 1 citation

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