Sep 2026
Glutathione-Driven Redox Inducer with Disruption of the SLC7A11/GSH/GPX4 Axis for Enhanced Ferroptotic Therapy
A glutathione-responsive metal–organic framework nanoplatform for the co-delivery of curcumin and a GPX4-targeting antisense oligonucleotide (ASO) demonstrated robust anticancer effects in 3D multicellular tumor spheroids with a promoted oxidative imbalance.
Sen Li, Wen-Tao Wang, Yi-Zhang Chen et al.
· Langmuir · 0 citations