Author

Sen Wu

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Open access Jul 2026

Dual-targeting CD73/PD-L1 bifunctional inhibitor: a promising cancer immunotherapy strategy

CP-1 exhibits balanced, dual-nanomolar inhibitory activity against PD-L1 and CD73 and displays potent immunomodulatory effects at the cellular level and serves as a promising lead candidate for developing novel bifunctional agents to advance tumor immunotherapy.

Jing-Jing Du, Sen Wu, Shiyun Cheng et al. · Frontiers in Immunology · 0 citations