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Seong-Ho Koh

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Open access Oct 2026

miR‐214‐3p and NCKAP1: A microglial functional dimension of Alzheimer's progression

Abstract INTRODUCTION Biological Alzheimer's disease (AD) pathology does not fully explain the marked heterogeneity in clinical severity or progression. We investigated whether patient‐derived induced microglia‐like cell (iMG) profiles capture a functional dimension of AD progression beyond conventional plasma biomarke...

Min-Young Noh, Yeonsil Moon, Sung-Woo Kang et al. · 0 citations
Editorial Open access Aug 2026

Beyond Amyloid: Hippocampal Atrophy as a Prognostic Marker in Amyloid-Negative Subjective Cognitive Decline

The emergence of blood-based biomarkers (BBMs) has transformed the diagnosis of Alzheimer’s disease (AD). 1,2 Plasma phosphorylated tau, glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) have demonstrated remarkable accuracy in detecting amyloid pathology and predicting disease progression acr...

H. Kwon, Seong-Ho Koh · 0 citations
Open access Aug 2026

Effects of Curcumin on Inflammation in a Rat Model of Diabetic Retinopathy

In diabetic rats, oral administration of a curcumin-containing formulation was associated with fewer retinal vascular abnormalities and lower GFAP immunoreactivity, accompanied by parallel differences in inflammasome-related proteins.

Hyoseon Yu, J. Kang, Seo Hyun Kim et al. · 0 citations
Jul 2026

Blood-based multimodal biomarker models for differentiating early-onset Alzheimer’s disease from frontotemporal dementia: a longitudinal study of early-onset dementia and family members (LEAF) study

Plasma p-tau217 and p-tau181 are effective biomarkers for distinguishing biologically defined EOAD from EOFTD and adding NfL, GFAP, and APOE ε4 status further improves the discriminative accuracy for differentiating EOAD from EOFTD.

H. S. Kwon, So Young Moon, Mina Hwang et al. · 0 citations

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