Author

Seong Soo A. An

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Review Open access Sep 2026

Resting-State EEG Microstate Dynamics as Neurophysiological Biomarkers Across the Alzheimer’s Disease Continuum: A Systematic Review

Electroencephalography microstates, brief periods of quasi-stable large-scale neural synchrony, have emerged as candidate markers of resting-state network disruption and show graded group-level differences across clinically defined SCD, MCI, and AD dementia samples.

Chanda Simfukwe, Seong Soo A. An, Y. Youn · Diagnostics · 0 citations

Review Open access Sep 2026

ERBB4 and Neurodegeneration: Association Between Hypothalamic–Pituitary–Adrenal (HPA) Axis: Associated Neurodegenerative Pathogenesis

The hypothalamic–pituitary–adrenal (HPA) axis is the central neuroendocrine system that controls physiological stress responses and maintains homeostasis through the coordinated interactions among the hypothalamus, pituitary gland, and adrenal cortex. Dysregulation of the HPA axis is associated with stress-related psyc...

Eva Bagyinszky, Seong Soo A. An · Cells · 0 citations

Review Open access Sep 2026

Small-Molecule NANT Therapeutics Targeting the Brain–Immune Axis in Alzheimer’s Disease: Mechanisms, Clinical Progress, and Translational Challenges

This review provided a general review of small molecules for neuroinflammation-based NANT therapies in AD and found that they all suffered from late-stage treatment, patient heterogeneity, inadequate central nervous system penetration, and poorly designed preclinical studies.

Niti Sharma, Seong Soo A. An · Molecules · 0 citations

Open access Jul 2026

EEG Microstate Alterations in Eyes-Open and Eyes-Closed Resting States Across the Alzheimer’s Disease Continuum

This study’s rEEG microstate analysis uncovered condition-dependent and disease-sensitive alterations across the HC, MCI, and AD groups, suggesting a more distributed disruption of network dynamics in advanced disease.

Chanda Simfukwe, Seong Soo A. An, Y. Youn · Journal of Clinical Medicine · 0 citations