Boosting Antitumor Activity: CuO Nanoparticles Enhance Pemetrexed Efficacy and Increase hsa-miR-548c-3p Expression in Human Lung Cancer
Background and objective — Lung cancer, particularly non-small cell lung cancer (NSCLC), is a leading cause of cancer-related death. Pemetrexed (PEM) is recognized as an effective chemotherapy drug. However, its efficacy is often compromised by resistance and side effects. Copper oxide nanoparticles (CuO NPs) are promi...