Aug 2026
Understanding Fibroblast Growth Factor-Heparan Sulfate Recognition by Molecular Dynamics Approaches.
It is concluded that, depending on the 6-O-sulfation pattern and the length of the oligosaccharide, either predominantly electrostatic interactions or a more complex interplay between electrostatic and hydrophobic interactions determines the specificity of the resulting protein-glycosaminoglycan complex.
Sergey A. Samsonov, A. Sieradzan, Avner Yayon
· Glycobiology · 0 citations