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Author

Serpil Aygörmez

3 papers indexed here

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Sep 2026

Insights into the protective role of trigonelline in 5-fluorouracil-induced lung injury: targeting oxidative stress, inflammation, and apoptosis.

5-Fluorouracil (5-FU) is an effective chemotherapeutic agent; however, its clinical use is frequently limited by toxicity in normal tissues, including the lungs. This study investigated the prophylactic protective effect of trigonelline (TRIG), a naturally occurring alkaloid, against 5-FU-induced pulmonary injury, with...

Hamit Uslu, Gözde Atila Uslu, T. Çoban et al. · 0 citations
Jul 2026

Betaine Alleviates Favipiravir-induced Ovarian and Uterine Toxicity by Regulating Oxidative, Inflammatory, Cellular Death, Steroidogenic, Hormonal, and Histopathological Changes

FVP caused multifaceted oxidative, inflammatory, apoptotic, and hormonal damage in ovarian and uterine tissues, while BTN significantly reduced these effects, preserving tissue integrity and function.

R. Bülbül, Hasan Şimşek, N. Akaras et al. · 0 citations

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