Effects of vasopressor dose on microcirculation despite preserved macrohemodynamic targets in septic shock: a prospective observational study.
BACKGROUND Septic shock may be complicated by hemodynamic incoherence, in which macrohemodynamic targets are achieved despite persistent microcirculatory alterations. Whether norepinephrine requirement is associated with dynamic microvascular reactivity after initial resuscitation, and whether central venous oxygen sat...