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Author

Seth M. Tomchik

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Open access Jul 2026

Loss of neurofibromin alters adult metabolism via effects during a developmental critical period

Data suggest that loss of Nf1 alters adult metabolism via effects during a critical period of nervous system development, and high-resolution respirometry on adult mitochondria revealed no differences in complex I/II function or fatty acid oxidation between nf1 mutants and controls.

Catherine Steele, Ryan J. Weaver, Seth M. Tomchik · 0 citations
Open access Aug 2026

N-acetylcysteine suppresses retinal defects in Drosophila models of SNRNP200-associated retinitis pigmentosa.

A new genetic model for studies of splicing-factor associated RP is established that recapitulates aspects of the human disease and suggests that antioxidants might serve as a treatment for individuals with SNRNP200-associated RP.

Sara K. Mayer, Quinton H Christensen, Hailey McCoy-Munger et al. · 0 citations

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