Open access
Aug 2026
Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics
It is argued that the convergence of geometric logic with automated synthesis and AI‑driven design will transform peptidomimetics into a primary modality for decoding and therapeutically engaging the human interactome, including historically "undruggable" PPIs.
Jesang Lee, Sumin Son, J. Y. Yoo et al.
· Angewandte Chemie · 0 citations