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Author

Seung-Tae Lee

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4 papers indexed here

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Open access Oct 2026

Clinical Evaluation of the Utility of Machine Learning-Based Subtype Classifiers of Acute Lymphoblastic Leukemia in Identifying Cryptic and Novel Fusions.

Background B-acute lymphoblastic leukemia (B-ALL) is a heterogeneous disease comprising more than 20 molecular subtypes defined by distinct gene expression profiles (GEPs) and genetic alterations. Subtypes primarily defined by GEPs remain challenging to identify using conventional cytogenetic and targeted molecular ass...

Seoyoung Lim, Yu Jeong Choi, Yu Jin Park et al. · 0 citations
Open access Sep 2026

Prognostic Value and Longitudinal Dynamics of Multigene Circulating Tumor DNA in Advanced Pancreatic Cancer Treated with 5-Fluorouracil-Based Chemotherapy

Circulating tumor DNA (ctDNA) is a minimally invasive biomarker in pancreatic ductal adenocarcinoma (PDAC), but the prognostic information added by multigene ctDNA metrics beyond KRAS and carbohydrate antigen 19-9 (CA19-9) is uncertain. In this prospective observational pilot study, 51 patients with advanced PDAC recei...

Gi-Ye-On Lee, Jung Won Chun, Dong-eun Lee et al. · 0 citations
Sep 2026

EYS-associated retinal degeneration in South Korea: Genetic, Phenotype, and Natural History.

PURPOSE To delineate the clinical and genetic spectrum of EYS-associated retinal degeneration (EYS-RD) and to quantify longitudinal progression of retinal structure and visual function. DESIGN, SETTING, AND PARTICIPANTS Multicenter retrospective cohort study at eight tertiary referral centers in South Korea, enrollin...

Jehwi Jeon, Dongheon Surl, H. Park et al. · 0 citations
Open access Aug 2026

Comprehensive High-Sensitivity Mutation Profiling in MPNs: Diagnostic and Prognostic Implications

Overall, the findings suggest that panel-based ultra-deep NGS improves mutation detection, enhances diagnostic sensitivity, and may provide valuable prognostic information for MPN management, although larger prospective studies are needed to confirm these results.

Namsoo Kim, Yehyun Kang, H. W. Kook et al. · 0 citations

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