Organotin-Catalyzed Synthesis, Characterization, Anticancer and Antioxidant Activities, and Molecular Modeling Studies of Nimesulide Ureas as Potential MetAP (Type II) Inhibitors
In this study, a new series of nimesulide-derived ureas (3a–j) was designed and synthesized to investigate structural modifications of nimesulide and to evaluate their biological activity. The compounds were obtained in high yields (68–88%) under organotin-catalyzed conditions, and their structures were unequivocally e...