Author

Sha Cheng

h-index 7 View on Semantic Scholar

We have 3 of 38 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Aug 2026

Prdx2 suppresses the erythroid differentiation by modulating the ROS-JNK1 signaling axis.

Erythroleukemia is a rare but aggressive subtype of acute myeloid leukemia with a poor prognosis and limited therapeutic options. Impaired erythroid differentiation is a hallmark of this disease, yet the underlying molecular mechanisms remain incompletely understood. Peroxiredoxin 2 (PRDX2), a key antioxidant enzyme in...

Dan Xie, Mingyue Yang, Sha Cheng et al. · Biochimica et Biophysica Act... · 0 citations

Open access Jul 2026

A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms

KZL-064 is identified, a 2-trifluoromethyl-4-aminoquinazoline derivative, which markedly inhibits HCC cell proliferation, migration, and invasion, induces apoptosis and G2/M arrest, and oral administration achieves tumor suppression comparable to that of sorafenib without significant toxicity.

Shi-Mei Wang, Xudong Cui, Gang Yu et al. · iScience · 0 citations

Jul 2026

Design, synthesis, and anti-prostate cancer activity evaluation of novel thieno[2,3-b]pyridine derivatives as potential BLM helicase inhibitors.

Nine novel thieno[2,3-b]pyridine derivatives were rationally designed and synthesized based on a versatile key intermediate, representing a promising lead compound for the development of novel BLM-targeted anti-prostate cancer agents.

Wei Tu, Ningning Zan, Xinyu Liu et al. · Molecular diversity · 0 citations