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Author

Sha-Hin I. Mai

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Review Open access Jul 2026

Unlocking new antimicrobial leads in the last decade: exploring quinolin-2-one based hybrids' synthesis, action, SAR, and challenges in tackling antimicrobial resistance.

Quinolin-2-one derivatives demonstrated considerable therapeutic promise as versatile antimicrobial scaffolds, but current studies revealed several limitations, including poor aqueous solubility, insufficient preclinical ADMET characterization, and limited in vivo validation.

M. A. Khattab, Sha-Hin I. Mai, A. Taher et al. · 0 citations

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