Shabnam Jampour Kolour

Multi-technique spectroscopic and computational modeling approaches for elucidation of the binding mechanism between two disperse azo dye derivatives and DNA.

Using multi-spectroscopy and molecular docking techniques, the binding mechanism between two azo dyes and the calf thymus (Ct-DNA) was investigated under physiological settings. After the addition of Ct-DNA, each azo dye exhibited a hypochromic effect and slightly increased the wavelength of the maximum absorption. Thi...