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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shahper Nazeer Khan

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Review Open access Oct 2026

Epigenetic Memory in Human Diseases: Acquired Chromatin States as Targetable Drivers of Disease Evolution

Clinical heterogeneity remains a major challenge across human diseases, where patients with similar genetic backgrounds frequently exhibit striking differences in disease progression, therapeutic response and clinical outcome. Increasing evidence indicates that these differences cannot be explained by genetic variation...

Shahper Nazeer Khan, Danishuddin, Salamatu Tijjani Isah et al. · 0 citations
Review Sep 2026

A cellular Digital Twin framework for predictive and mechanistic modeling of drug responses in precision medicine.

Biomedical Digital Twins (DTs) are emerging as a significant concept in precision health and drug discovery, enabling dynamic, high-resolution representations of patients through the real-time integration of multimodal datasets. While most studies focus on organ or patient-level models, accurate prediction of drug resp...

Danishuddin, M. Haque, G. Madhukar et al. · 0 citations

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