A Signal Turn-On DNA Proximity Assay That Correlates with SARS-CoV-2 Blocking Antibody Levels
Surrogate in vitro assays have enabled the scalable testing of neutralizing antibodies to SARS-CoV-2 as a toolbox to manage the post-COVID-19 situation and future outbreaks. However, most surrogate assays use a competitive format to mimic the blocking event between the receptor binding domain (RBD) and the human angi...