Sep 2026
Automated Multimodal Correlative Registration for Organelle-Specific Elemental and Isotopic Imaging.
Mapping the subcellular partitioning of therapeutics is important for understanding their trafficking, mechanisms of action, and off-target effects. NanoSIMS provides chemical images of labeled therapeutics, but assigning these signals to cellular structures requires correlation with electron microscopy (EM). This corr...
Chi-Xiang Lu, Kai-Qiang Zhao, D. Cui et al.
· Analytical Chemistry · 0 citations