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Shan-Qi Xu

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Open access Aug 2026

Luteolin-7-O-rutinoside alleviates rheumatoid arthritis through downregulation of the PI3K/AKT/NF-κB and cell cycle signaling pathways

It is demonstrated that lut-7-O-rutin alleviates joint inflammation and synovial hyperplasia in RA may be mediated through inhibiting the PI3K/AKT/NF-κB signaling pathway and downregulating cell cycle-associated proteins, highlighting its potential as a therapeutic agent for RA.

Wei-Xi Liu, Xian Jiang, Shan-Qi Xu et al. · Frontiers in Pharmacology · 0 citations