Aug 2026
HiHPO: Multimodal Hierarchical Graph Learning for Predicting Missing Protein-Phenotype Associations.
HiHPO is proposed, a multimodal, hierarchy-aware graph contrastive learning framework for predicting protein-phenotype associations that consistently outperforms state-of-the-art methods and preserves semantic relationships among phenotypes and improves generalization to fine-grained and sparsely annotated terms.
Hancheng Liu, W. Zhai, Shaojun Wang et al.
· IEEE journal of biomedical a... · 0 citations