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Shang-Cheng Hung

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Aug 2026

Liquid biopsy-based detection of circulating and exfoliated cholangiocarcinoma tumor cells from blood and bile using heparan sulfate octasaccharides on integrated microfluidic systems.

Early diagnosis of cholangiocarcinoma (CCA) remains challenging because existing diagnostic approaches often lack sufficient sensitivity for reliable detection of early-stage disease. Circulating tumor cells (CTCs) in blood and exfoliated tumor cells (ETCs) in bile represent valuable targets for liquid biopsy-based det...

Wei-Chun Tsai, Anandaraju Bandaru, Cheng-Hsiu Chang et al. · 0 citations
Review Open access Aug 2026

Recent advances in the chemical synthesis of Glycosaminoglycans.

Glycosaminoglycans (GAGs) are complex carbohydrates ubiquitously expressed on cell surfaces and within the extracellular matrix, where they regulate essential biological processes through sequence- and sulfation-dependent interactions. Major GAG classes, including heparan sulfate (HS), chondroitin sulfate (CS), dermata...

Jasper S Dumalaog, Shang-Cheng Hung · 0 citations

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