Open access
Oct 2026
Glycosaminoglycan-Based CD44-Targeted Nanoparticles for Cancer Therapy: Biological Barriers and Barrier-Informed Design Strategies
Nanoparticle (NP)-based drug delivery has been explored to improve the therapeutic index of anticancer agents by enhancing tumor accumulation and reducing systemic toxicity. Among active targeting approaches, cluster of differentiation 44 (CD44) has attracted attention because of its overexpression in tumor cells and...
Shang-Yu Chen, Sheida Dabiri, Yi-Chen Xu et al.
· Nano letters (Print) · 0 citations