Open access
Aug 2026
Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo
An efficient Cas9d system (Cas9dUltra) is developed through gRNA and protein engineering, and its base editors (9dBEs) further developed through gRNA and protein engineering, enabling efficient and precise genome editing in human cells.
Qingquan Xiao, Zhijin Tian, Luqi Weng et al.
· Advancement of science · 0 citations