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Author

Shanshan Cheng

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Open access Aug 2026

Label-free ovarian cancer histopathological diagnosis using two-photon autofluorescence microscopy with a joint denoising and segmentation framework

Two-photon autofluorescence (TPAF) microscopy is a promising modality for rapid, label-free assessment of unstained tissue, but is fundamentally limited by the poor visibility of nuclei, which are one of the gold-standard cancer biomarkers, due to their negative contrast nature. A restoration method capable of distingu...

Zhengyuan Pan, Naikun Song, Shanshan Cheng et al. · 0 citations

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