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Author

Shao-Hui Wang

2 papers indexed here

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Open access Sep 2026

Complete disruption of gD binding to HVEM alters virus replication and host receptor homeostasis

Herpes simplex virus 1 (HSV‑1) establishes infection through coordinated interactions of multiple viral glycoproteins with host cell receptors. Interactions between the viral glycoprotein D (gD) and the immunomodulatory cellular receptor HVEM (herpesvirus entry mediator) critically influence HSV‑1 latency and reactivat...

Deepak Arya, Kati Tormanen, Jay J. Oh et al. · 0 citations
Open access Sep 2026

Epigenetic profiling reveals M1 macrophages as the primary drivers of trained immunity in HSV-1 latently infected mice

Macrophages play multifaceted and critical roles in controlling diverse pathogenic infections. Building on our recently published observations of macrophages exhibiting memory responses to HSV-1 infection, our current report investigates the macrophage subtype responsible for generating trained immunity against virus-i...

Ujjaldeep Jaggi, Shao-Hui Wang, H. Ghiasi · 0 citations

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