Dual role of ferroptosis in embryonic development, cascade amplification regulatory mechanism and targeted intervention
Ferroptosis is an iron-dependent regulated cell death driven by lipid peroxide accumulation. This review discusses its dual role in embryonic development. Physiologically, ferroptosis regulates cell fate and tissue remodeling through the synergistic GPX4-GSH and FSP1-CoQ10 pathways. Beyond passive cell death, iron-depe...