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Author

Shaoting Zhang

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Preprint Aug 2026

EviDx: Evidence-Aware Active Diagnosis with Scaffolded LLM Agents

EviDx is introduced, an evidence-aware active diagnosis framework that pairs patient-specific diagnostic environments with a clinical diagnostic scaffold and an observer-guided runtime harness that improves diagnostic performance and process stability while revealing model-dependent capability boundaries.

Lihang Zeng, Shao-Ting Zhang, Xiaofan Zhang · 0 citations
Preprint Jul 2026

Reinforcement Learning for Evidence-Seeking Diagnostic Reasoning with Large Language Models

Empirical results demonstrate that the Reinforcement Learning with Verifiable Rewards framework enables LLMs to transition from passive responders to autonomous assistants, and demonstrates comparable performance to larger and reasoning-enhanced baselines, while RAGES proves superior to vanilla LLMs in generating biolo...

Shengyi Hua, Kangzhe Hu, Conghui He et al. · 1 citation
Jul 2026

RareLens: Towards End-to-End Rare Disease Care via Aligning Divergent Large Language Model Reasoning

Autonomous RareLens and physicians assisted by RareLens both outperformed unaided physicians, while demonstrating that effective human-AI collaboration requires more than simply providing model outputs, and suggest a general strategy for building AI systems that operate reliably under high clinical uncertainty.

Xi Chen, Hong-Ru Zhou, Shi-Yu Feng et al. · 0 citations

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