Integrated multi-omics analysis reveals shared IFN-γ-associated monocyte signatures in primary Sjögren’s syndrome and Alzheimer’s disease
Primary Sjögren’s syndrome (pSS) is epidemiologically associated with an increased risk of Alzheimer’s disease (AD); however, the shared IFN-γ-related immune mechanisms underlying this association remain poorly understood. Peripheral blood transcriptomic, single-cell transcriptomic, and epigenomic datasets...