SCULPT-MCP: Systematic Chromosomal Upgrades for Locus-Driven Protein Topologies in Microcompartments.
Gene order is a powerful design principle for protein nanomachines. In nature, gene organization ensures the precise assembly of functional protein nanostructures. We demonstrate how the genetic repositioning of the key structural gene pduN within the operon encoding a self-assembling protein nanocompartment sculpts th...