Open access
Sep 2026
Analytical and Biological Factors Associated with Oncogenic Variant Yield in Tumor-Agnostic Plasma ctDNA Profiling
Background/Objectives: Tumor-agnostic plasma ctDNA profiling is used when tumor tissue is unavailable, insufficient, or unrepresentative. We investigated analytical and biological factors associated with oncogenic variant yield. Methods: In the prospective EXMASTER study, plasma cfDNA was analyzed using a 265-gene targ...
Stephen George, L. Ranganathan, Yi-Zhen Xiang et al.
· Diagnostics · 0 citations