Adolescence is a developmentally sensitive interval in which linear growth, pubertal endocrine maturation, body-composition change, and rapid skeletal mineral accrual occur while experimentation with nicotine, tobacco, and cannabis commonly begins. This critical narrative review evaluates whether exposure to combustibl...
Ashraf T. Soliman, F. Alyafei, Nada Alaaraj et al.· Journal of Scientific Resear...· 0 citations
Abstract Longitudinal bone growth in children depends on endochondral ossification within the epiphyseal growth plate, a process long viewed as a passive readout of systemic hormones but now recognized as an actively regulated, self-limiting process. This mini-review synthesizes recent evidence on chondrocyte biology,...
Ashraf T. Soliman, F. Alyafei, Nada Alaaraj et al.· Journal of Pediatric Endocri...· 0 citations
Quantitative analysis reveals that fetal programming and adipose tissue development are the predominant mechanisms, but endocrine, epigenetic, and environmental factors also play significant roles, and underscore the need for mechanistic-based risk assessments in clinical practice to guide early interventions in at-ris...
Fawziya Alyafei, Ashraf T. Soliman, A. Elawwa et al.· European Journal of Endocrin...· 0 citations
A tiered, genotype-informed approach—combining HPLC/CE phenotyping, targeted molecular diagnostics, genetic modifier profiling, and periodic re-evaluation—optimizes diagnostic precision and guides individualized management across the thalassemia spectrum.
Ashraf T. Soliman, F. Alyafei, Nada Alaaraj et al.· Thalassemia Reports· 0 citations
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