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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Shengkun Li

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Aug 2026

Scaffold Hopping of Florylpicoxamid for Structurally and Biologically Distinct Antifungal Leads.

Simplification of the complex macrolide UK-2A delivers florylpicoxamid, while optimization of its synthetically challenging pyridinyl acid remained underdeveloped. Scaffold hopping with 14 structurally distinctive heterocyclic acids in the molecular evolution of florylpicoxamid led to thiazole amide as a novel antifung...

Wenlong Kong, Pengzhi Sun, Xian Ming et al. · 0 citations

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