Open access
Sep 2026
Immune remodeling and myeloid signature in the bone marrow niche of MYCN-driven neuroblastoma
High-risk MYCN-amplified neuroblastoma is associated with a dire prognosis and often metastasizes to the bone marrow. However, systemic immune remodeling and its effect on the bone marrow niche remain unclear. Harnessing single-cell RNA sequencing, we compare the bone marrow immune cell landscape of wild-type (WT) mice...
Bethel Tesfai Embaie, A. Alchahin, Lilly Velentza et al.
· BJC Reports · 0 citations