Reticulocalbin‐2–Programmed Macrophage Exosomes Restore Immuno‐Osteogenic Coupling to Promote Calvarial Bone Regeneration
Calvarial defect repair is frequently limited by immune dysregulation and insufficient coupling with bone regeneration. This study investigated the regulatory role of reticulocalbin‐2 (RCN2) in macrophages and evaluated a biomimetic periosteum‐bone bilayer scaffold (PB‐BLS) designed to deliver RCN2‐modified M2 macropha...