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Review Open access Aug 2026

Exercise as a multimodal intervention for adolescent depression: integrating neuroplasticity, BDNF signaling, stress biomarkers, exercise intensity, digital mental health interventions, and precision psychiatry

The overall evidence supports exercise as a promising complementary or preventive approach for adolescent depression, and future research should prioritize standardized methodologies, longitudinal designs, and mechanistic investigations to strengthen causal inference and translational applicability.

Ji-Qiao He, Sheng Zhu, Jiahong Luo et al. · 0 citations

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