Abstract B063: A gene-editable human regulatory T-cell platform reveals USP22 as a regulator of FOXP3 stability and IFN-γ production
Regulatory T cells (Tregs) are key modulators of immune responses and are increasingly targeted for their therapeutic potential in hematologic malignancies, autoimmune diseases, and immune-mediated complications of hematopoietic cell transplantation. Robust human Treg assays are therefore essential to evaluate no...