Open access
Oct 2026
An engineered probiotic for diagnosis and mucosal healing in inflammatory bowel disease.
An integrated probiotic platform for IBD diagnosis and regenerative therapy is established, replacing the diagnostic output of the ROS-responsive circuit with IL-22-Fc enables inflammation-triggered therapeutic delivery and significantly alleviates colitis.
Yu Zhao, Yu-Jie Sun, Xiao-Feng Zhu et al.
· Cell Reports · 0 citations