Author

Shi-Hong Chen

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Open access Oct 2026

PPAR-γ/SGK1/GSK3β/Nrf2 signaling pathway contributes to the neuroprotective effects of lycopene in depressed mice.

INTRODUCTION Major depressive disorder (MDD) is a neuropsychiatric disorder associated with abnormal neuronal activity in specific brain regions. Recent evidence suggests that oxidative stress- and neuroinflammation-driven impairments in synaptic structure and neuronal function may contribute to depression, yet the pre...

Yong-Si Zhao, Meng-Ni Chang, Cheng-Xin Hu et al. · Journal of Advanced Research · 0 citations

Open access Jul 2026

Single cell transcriptomics analyses reveal functional heterogeneity and anti-tumor role of mast cells in esophageal squamous cell carcinoma

The findings demonstrate that MCs exhibit distinct functional states in ESCC and regulate tumor progression and support their potential relevance in immunotherapy.

Yiren Huang, Zheyi Chen, Bingqian Zhou et al. · Frontiers in Immunology · 0 citations