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Shi-Long Li

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Review Open access Sep 2026

Dual role of ferroptosis in embryonic development, cascade amplification regulatory mechanism and targeted intervention

Ferroptosis is an iron-dependent regulated cell death driven by lipid peroxide accumulation. This review discusses its dual role in embryonic development. Physiologically, ferroptosis regulates cell fate and tissue remodeling through the synergistic GPX4-GSH and FSP1-CoQ10 pathways. Beyond passive cell death, iron-depe...

Fan Meng, Shi-Long Li, Xue-Ting Wang et al. · 0 citations

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