Author

Shi-Ping Zhang

2 papers indexed here

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Sep 2026

Expanded Polyglycine Protein Aggregates Alter the RNA Splicing Profile into a Premature State Partially via Sequestering SF3B4.

This study suggests that polyG protein aggregates in NIID may shift the global RNA splicing profile toward an immature state, potentially through the sequestration of key splicing factors, such as SF3B4, thereby identifying new avenues for understanding the pathogenic mechanisms underlying NIID.

Jia-Xin Yang, You-Qi Zheng, Jian-Yi Hu et al. · Neuroscience Bulletin · 0 citations

Open access Jul 2026

VAMP7-dependent mitochondria-lysosome contacts contribute to glial mitochondrial dynamics and dopaminergic neuron survival.

Although disrupted mitochondrial dynamics in neurons are closely linked to neurodegenerative diseases, far less is known about how mitochondrial dynamics are regulated in glia or whether glial mitochondrial dysfunction contributes to neurodegeneration. Here, we show that the R-SNARE protein VAMP7 regulates the untether...

Honglei Wang, Mengxiao Wang, Yu-ting Tsai et al. · Proceedings of the National... · 2 citations