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Shi-Qin Jiang

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Nov 2026

Reversal of acquired osimertinib resistance by YAP inhibition in lung cancer is associated with lipid metabolic reprogramming.

Osimertinib (Osi), as the third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), has demonstrated remarkable efficacy in the treatment of non-small cell lung cancer (NSCLC). However, recent studies have found that its acquired resistance severely limits its therapeutic effect. This stud...

Jun-Yuan Huang, Yin-Huang Gao, Shi-Qin Jiang et al. · 0 citations

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