Author

Shi-Xiong Zhang

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Open access Oct 2026

Reversal of Chronic Stress‐Induced Inflammaging by Bazi Bushen Formula Through AMPK‐Sirtuins Axis Activation and Myeloid Reset

ABSTRACT Chronic stress potentially accelerates aging and increases age‐related disease risk. However, the underlying mechanisms and organ specificity remain unclear. Utilizing a 12‐month unpredictable chronic mild stress (UCMS) mouse model, we revealed chronic stress significantly exacerbates systemic inflammation, ca...

Meng-Nan Li, Zhe-Ming Chen, Lu Wang et al. · Exploration · 0 citations

Oct 2026

Study of the Mechanism of Xianglian Anchang Decoction Ameliorating Ulcerative Colitis Based on Transcriptomics and Network Pharmacology Analysis.

INTRODUCTION The therapeutic efficacy of Xianglian Anchang Decoction (XLAC) in Ulcerative Colitis (UC) has been established, but the underlying pharmacological mechanisms have remained poorly elucidated. In this study, we employed an integrated strategy combining network pharmacology, transcriptomic profiling, and in v...

Tian-Yu Gao, Cui-Mei Zhao, Li-Sha Lu et al. · Combinatorial chemistry & hi... · 0 citations